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The heart is an electrically controlled and chemically powered mechanical pump. There are complex interactions between cardiac electrophysiology, metabolism, and mechanics, with a multitude of interdigitating regulatory loops. This chapter will focus on the cross-talk between electrical and mechanical activity of the heart, and in particular its relevance for heart rhythm. © 2008 Springer-Verlag London Limited.

Original publication





Book title

Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Prevention

Publication Date



145 - 160