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Neurons usually migrate and differentiate in one particular encephalic vesicle. We identified a murine population of diencephalic neurons that colonized the telencephalic amygdaloid complex, migrating along a tangential route that crosses a boundary between developing brain vesicles. The diencephalic transcription factor OTP was necessary for this migratory behavior.

Original publication

DOI

10.1038/nn.2556

Type

Journal article

Journal

Nat Neurosci

Publication Date

06/2010

Volume

13

Pages

680 - 689

Keywords

Amygdala, Animals, Cell Count, Cell Movement, Diencephalon, Electroporation, Homeodomain Proteins, Hypothalamus, Immunohistochemistry, In Situ Hybridization, In Vitro Techniques, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Nerve Tissue Proteins, Neurons, RNA Interference, Stem Cell Niche, Telencephalon