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The role of the CB1 cannabinoid receptor and endocannabinoid signalling has been widely studied in the adult nervous system. However, an emerging body of evidence suggests that the CB1 receptor may also play a role during development. Here we have scrutinized the expression profile of the CB1 receptor from the onset of neurogenesis in the chick embryo. We find that this gene exhibits a dynamic expression pattern that spatially and temporally follows neuronal differentiation in the early embryo.

Original publication




Journal article


J Anat

Publication Date





213 - 218


Animals, Cell Differentiation, Chick Embryo, Immunohistochemistry, In Situ Hybridization, Nervous System, Neurons, Receptor, Cannabinoid, CB1