Biomimetic materials: Peptide-directed spatial organization of biomolecules in dynamic gradient scaffolds (adv. Healthcare mater. 9/2014).
Chow LW., Armgarth A., St-Pierre JP., Bertazzo S., Gentilini C., Aurisicchio C., McCullen SD., Steele JA., Stevens MM.
Peptide-polymer conjugates that specifically and dynamically bind glycosaminoglycans are used to functionalize the surface of biodegradable electrospun fiber scaffolds. The versatile platform presented by L. W. Chow, M. M. Stevens, and colleagues on page 1381 can be used to recreate gradients of ECM-like biomolecule organization within scaffolds to achieve more functional and clinically relevant tissue-engineered constructs.