Fast, volumetric imaging of in vivo mouse brain with swept confocally aligned planar excitation (SCAPE) microscopy
Voleti V., Bouchard MB., Lacefield C., Bruno R., Hillman EMC.
We demonstrate the use of SCAPE microscopy to image both neural activity via GCaMP and vascular hemodynamics in the awake behaving mouse brain at 10-20 volumes per second with cellular resolution over large fields of view. The performance of SCAPE is compared to in-vivo two-photon microscopy.