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A model of the coupled electro-mechanics of cardiac tissue is presented. The cell model is incorporated into a 2D tissue model in which the equations of large deformation tissue mechanics are solved by Galerkin finite element techniques and electrical wave propagation is solved with a high resolution finite difference grid based on material points embedded in the mechanically defoming tissue. The extracellular tissue mechanics model includes the nonlinear, anisotropic passive elastic properties based in the underlying connective tissue microstructure.


Journal article


Annals of Biomedical Engineering

Publication Date