Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The signal acquired in sodium (23Na) MR imaging is proportional to the concentration of sodium in a voxel, and it is possible to convert between the two using external calibration phantoms. Postprocessing, and subsequent analysis, of sodium renal images is a simple task that can be performed with readily available software. Here we describe the process of conversion between sodium signal and concentration, estimation of the corticomedullary sodium gradient and the procedure used for quadrupolar relaxation analysis.This chapter is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This analysis protocol chapter is complemented by two separate chapters describing the basic concept and experimental procedure.

Original publication

DOI

10.1007/978-1-0716-0978-1_41

Type

Chapter

Publication Date

2021

Volume

2216

Pages

689 - 696

Keywords

23Na, Kidney, Magnetic resonance imaging (MRI), Rats, Sodium, Animals, Contrast Media, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Kidney, Magnetic Resonance Imaging, Monitoring, Physiologic, Phantoms, Imaging, Rats, Sodium Isotopes, Software