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Innervation of the neocortex by the thalamus is dependent on the precise coordination of spatial and temporal guidance cues. In this issue of Cell, work by López-Bendito et al.(2006) reveals that tangentially migrating cells within the ventral telencephalon are essential for axonal navigation between the thalamus and the neocortex, a process apparently mediated by Neuregulin-1/ErbB4 short- and long-range signaling.

Original publication

DOI

10.1016/j.cell.2006.03.021

Type

Journal article

Journal

Cell

Publication Date

07/04/2006

Volume

125

Pages

24 - 27

Keywords

Animals, Axons, Cell Movement, Cerebral Cortex, ErbB Receptors, Neuregulin-1, Receptor, ErbB-4, Signal Transduction, Thalamus