Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Intrinsic genetic differences and extrinsic influences both contribute to the formation of functional and anatomical areas within the mammalian cerebral cortex. Using subtractive hybridisation and differential screening, we demonstrated that plasticity-related gene-3 (PRG-3) is differentially expressed between the dorsal and lateral cortex at P6. PRG-3 is one of the key enzymes that are involved in the metabolism of phospholipids, such as LPA and S1P, in the nervous system. Here, for the first time, we report the mRNA expression pattern of PRG-3 in the developing and adult mouse cerebral cortex.

Original publication




Journal article


Brain Res Bull

Publication Date





454 - 460


Age Factors, Animals, Animals, Newborn, Blotting, Southern, Cerebral Cortex, Cloning, Molecular, Embryo, Mammalian, Eosinophil Major Basic Protein, Gene Expression, Gene Expression Regulation, Developmental, In Situ Hybridization, Mice, Mice, Inbred C57BL, RNA, Messenger