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The Anterior Visceral Endoderm is an extraembryonic tissue that plays a pivotal role during embryogenesis, being responsible for the proper orientation of the anterior-posterior axis of the embryo and for appropriate pattering of adjacent embryonic tissue. In this review I discuss the formation and migration of the AVE, and attempt to place some recent findings in the context of a working model.

Original publication

DOI

10.1002/dvg.20249

Type

Journal article

Journal

Genesis

Publication Date

11/2006

Volume

44

Pages

565 - 572

Keywords

Animals, Body Patterning, Cell Movement, Endoderm, Extraembryonic Membranes, Mice, Models, Biological