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In this issue of Developmental Cell, Hashimoto and Sasaki (2019) explore the role of the Hippo pathway in the establishment of naive pluripotency and cell competition in the epiblast. Their work gives insight into how the mouse embryo selects cells with the highest future potential, through the activity of YAP/TEAD.

Original publication

DOI

10.1016/j.devcel.2019.07.005

Type

Journal article

Journal

Dev Cell

Publication Date

22/07/2019

Volume

50

Pages

127 - 128

Keywords

Animals, Germ Layers, Mice, Protein-Serine-Threonine Kinases, Signal Transduction, Transcription Factors