Postdoctoral Research Scientist
I completed my undergraduate training in Biotechnology (Bachelor & Honours) at the University of Newcastle (UoN). I then completed a PhD in medicine, established as a first of its kind international collaboration between UoN and the Medical University of Graz, Austria. This cardiovascular research project focussed on understanding the role of novel crosstalk between inflammation and fibrosis throughout wound healing after myocardial infarction. I was most recently appointed as Postdoctoral Research Scientist at Prof Paul Riley’s research group at the University of Oxford; a project funded by the British Heart Foundation. I was also awarded a Junior Research Fellowship by the St. John’s College of Oxford University, funding an independent research programme beginning October 1, 2023. My current work is utilizing translational models to trial the therapeutic potential of stimulating angiogenesis and lymphangiogenesis after myocardial infarction to ameliorate the fibrotic response, minimize tissue damage, and improve cardiac outcomes.
Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction
Murtha LA. et al, (2023), Nature: Scientific Reports
Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction
Hardy S. et al, (2023), JACC: Basic to Translational Science
Paracrine Factors Released by Stem Cells of Mesenchymal Origin and their Effects in Cardiovascular Disease: A Systematic Review of Pre-clinical Studies.
Mabotuwana NS. et al, (2022), Stem Cell Rev Rep, 18, 2606 - 2628
Small molecule STING inhibition improves myocardial infarction remodeling.
Rech L. et al, (2022), Life Sci, 291
STING inhibition in myocardial remodelling following myocardial infarction
Rech L. et al, (2021), European Heart Journal, 42