CBE, DBE, F.MedSci., FRS
Dr Lee’s Professor of Anatomy Emeritus
Kay Davies was an undergraduate at Somerville College and a Junior Research Fellow at Wolfson College, Oxford. She was elected as Dr Lee’s Professor of Anatomy at the University of Oxford in 1998. Professor Kay Davies was Head of Department from 2008 to 2011.
Her research interests lie in the molecular analysis of human genetic disease, particularly the genetic basis of neuromuscular and neurological disorders. She first became interested in muscular dystrophy more than 20 years ago and many of her research group are dedicated to finding effective treatments for Duchenne muscular dystrophy (DMD) and spinal muscular atrophy.
In 1999, she set up the MRC Functional Genomics Unit aimed at exploiting genome information for the analysis of the function of genes in the nervous system. In 2000, she co-founded the Oxford Centre of Gene Function with Professors Ashcroft (Physiology) and Donnelly (Statistics) to bring together genetics, physiology and bioinformatics in a new multidisciplinary building which was completed in 2003. She is co-director of this initiative. She is currently co-director of the MDUK Oxford Neuromuscular Centre.
She has an active interest in the ethical implications of her research and in the public understanding of science. She is a founding fellow of the Academy of Medical Sciences and was elected a Fellow of the Royal Society in 2003.
Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy.
Vuorinen A. et al, (2021), Eur J Med Chem, 220
Evaluating the potential of novel genetic approaches for the treatment of Duchenne muscular dystrophy.
Himič V. and Davies KE., (2021), Eur J Hum Genet
Highway to HHGE: An Interview with Dame Kay E. Davies.
Davies K. and Davies KE., (2020), CRISPR J, 3, 325 - 331
The Long Journey from Diagnosis to Therapy.
Davies KE., (2020), Annu Rev Genomics Hum Genet, 21, 1 - 13
From diagnosis to therapy in Duchenne muscular dystrophy.
Babbs A. et al, (2020), Biochem Soc Trans