Deputy Head of Department
- Director of Graduate Studies
- University Lecturer
Helen Christian gained a degree in Pharmacology in 1993 (University of Edinburgh) and a doctorate in Pharmacology in 1997 (University of London). She came to the Department of Human Anatomy, Oxford in 1996 funded by a one year post-doctoral fellowship before taking up a Departmental Lectureship in Human Anatomy in 1997. Since 2000 she has been a University Lecturer in Biomedicine and Fellow of St Anne’s College. She was awarded a University of Oxford Teaching Excellence Award in 2010 and an OxTalent award for innovative teaching in 2011.
Helen Christian's research interests are in the mechanisms of steroid hormone regulation of the pituitary gland, in particular the role of Annexin 1. The Annexins are a well conserved super-family of structurally related Ca2+ - and phospholipids-binding proteins with wide-ranging functions in health and disease. Annexin 1 is a 37kD protein that is induced by glucocorticoids and mediates glucocorticoid action within the host defence and neuroendocrine systems.
Disentangling juxtacrine from paracrine signalling in dynamic tissue.
Momiji H. et al, (2019), PLoS Comput Biol, 15
Ultrastructural Changes Within the Pituitary Associated with Reproductive Timing in a Hibernating Mammal
Duncan CM. et al, (2019), INTEGRATIVE AND COMPARATIVE BIOLOGY, 59, E305 - E305
Cell-Specific Loss of SNAP25 from Cortical Projection Neurons Allows Normal Development but Causes Subsequent Neurodegeneration.
Hoerder-Suabedissen A. et al, (2018), Cereb Cortex
Phenotypic dissection of the mouse Ren1d knockout by complementation with human renin.
Buckley C. et al, (2018), J Biol Chem, 293, 1151 - 1162
THE CARDIAC HEPCIDIN/FERROPORTIN AXIS IS ESSNTIAL FOR CARDIAC IRON HOMEOSTASIS AND FUNCTION
Lakhal-Littleton S. et al, (2017), HEART, 103, A137 - A137