Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2.
Journal article
Michl J. et al, (2023), Cell Rep, 42
CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH.
Journal article
Michl J. et al, (2022), Cell Rep, 38
BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.
Journal article
Tacconi EM. et al, (2017), EMBO Mol Med, 9, 1398 - 1414
Medicinally Used Asarum Species: High-Resolution LC-MS Analysis of Aristolochic Acid Analogs and In vitro Toxicity Screening in HK-2 Cells
Journal article
Michl J. et al, (2017), Frontiers in Pharmacology, 8
FANCD2 limits replication stress and genome instability in cells lacking BRCA2.
Journal article
Michl J. et al, (2016), Nat Struct Mol Biol, 23, 755 - 757
Interplay between Fanconi anemia and homologous recombination pathways in genome integrity.
Journal article
Michl J. et al, (2016), EMBO J, 35, 909 - 923
LC-MS- and 1H NMR-Based Metabolomic Analysis and in Vitro Toxicological Assessment of 43 Aristolochia Species
Journal article
Michl J. et al, (2016), Journal of Natural Products, 79, 30 - 37
Aristolochia species: A metabolomic and ethnopharmacological risk assessment focusing on local uses in Bangladesh
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Heinrich M. and Michl J., (2015), Toxicology Letters, 238, S32 - S33
A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities
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Michl J. et al, (2014), European Neuropsychopharmacology, 24, 1463 - 1474
Naturally occurring aristolochic acid analogues and their toxicities
Journal article
Michl J. et al, (2014), Natural Product Reports, 31, 676 - 676
Metabolomic Analysis of Ranunculus spp. as Potential Agents Involved in the Etiology of Equine Grass Sickness
Journal article
Michl J. et al, (2011), Journal of Agricultural and Food Chemistry, 59, 10388 - 10393