Research groups
Colleges
Mathilda Mommersteeg
Associate Professor of Developmental and Regenerative Medicine
- Deputy Director of Graduate Studies
I obtained my PhD in 2009 from the University of Amsterdam, where I worked in the laboratories of Prof. Vincent Christoffels and Prof. Antoon Moorman on the development of the conduction system and venous pole of the mammalian heart. In 2010, I joined the laboratory of Prof. John Parnavelas at University College London (UCL) as a long-term EMBO fellow. At UCL, my work focused on deciphering the roles of the Slit-Robo signalling pathway during mammalian heart development. While at UCL, I set up a project researching heart regeneration in Mexican cavefish together with dr. Yoshiyuki Yamamoto, which was sponsored by the British Heart Foundation in 2012. Both my post-doctoral projects form the basis for my current research interests in investigating the molecular mechanisms underlying heart regeneration and development.
Recent publications
Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development.
Preprint
Zhao J. et al, (2025)
Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development
Journal article
Zhao J. et al, (2025), eLife, 14
Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development
Preprint
Zhao J. et al, (2025)
Oxidative phosphorylation is required for cardiomyocyte re-differentiation and long-term fish heart regeneration.
Journal article
Lekkos K. et al, (2025), Nat Cardiovasc Res, 4, 1363 - 1380
Oxidative phosphorylation is required for fish heart regeneration.
Journal article
(2025), Nat Cardiovasc Res, 4, 1219 - 1220

