Contact information
+49 (0)761 270-63950
Institute for Experimental Cardiovascular Medicine, University of Freiburg
Peter Kohl
MD PhD FAHA FHRS FTPS FIUPS
Visiting Professor of Cardiovascular Physiology
Since 2016, I have been with Freiburg University, Germany, where I am fortunate to be allowed to set up and direct the Institute for Experimental Cardiovascular Medicine. The institute is part of the University Heart Centre – with more than 1,500 staff and 24,000 hospitalisations p.a. the largest such centre at German university hospitals. The Institute served as the bedrock for a national Collaborative Research Centre (akin to British Heart Foundation Centres of Research Excellence), bridging natural sciences, engineering, computing, and medicine to ‘make better scars’.
Before moving to Freiburg, I served as the Chair in Cardiac Biophysics and Systems Biology at the National Heart and Lung Institute, Imperial College London (2010-2015). Prior to that, I spent nearly two decades at DPAG, progressing from post-doctoral research fellow with Denis Noble, to principal investigator, lecturer and reader, holding various BHF and UKRC grants, a University Research Fellowship from the Royal Society, a Senior Fellowship from the BHF, and an ERC Advanced Grant.
My interests lie in cardiac structure-function studies, including myocytes and non-myocytes (structure) and bi-directional electro-mechanical cross-talk (function), which we explore utilising a mix of experimental and computational techniques.
Key publications
Disturbed Repolarization-Relaxation Coupling During Acute Myocardial Ischemia Permits Systolic Mechano-Arrhythmogenesis.
Journal article
Cameron BA. et al, (2025), Circ Res, 137, 363 - 382
Electron microscopy of cardiac 3D nanodynamics: form, function, future.
Journal article
Kohl P. et al, (2022), Nat Rev Cardiol, 19, 607 - 619
Beat-by-Beat Cardiomyocyte T-Tubule Deformation Drives Tubular Content Exchange.
Journal article
Rog-Zielinska EA. et al, (2021), Circ Res, 128, 203 - 215
Primary cilia defects causing mitral valve prolapse.
Journal article
Toomer KA. et al, (2019), Sci Transl Med, 11
Potassium channel-based optogenetic silencing.
Journal article
Bernal Sierra YA. et al, (2018), Nat Commun, 9
Macrophages Facilitate Electrical Conduction in the Heart.
Journal article
Hulsmans M. et al, (2017), Cell, 169, 510 - 522.e20
Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics.
Journal article
Quinn TA. et al, (2016), Proc Natl Acad Sci U S A, 113, 14852 - 14857
Recent publications
Channelrhodopsin Ion Selectivity Determines Mechanisms and Efficacy of Optogenetic Defibrillation in Human Atria and Ventricles
Preprint
Ohnemus S. et al, (2026)
Interstitial cells and arrhythmia.
Journal article
Rog-Zielinska EA. et al, (2026), Am J Physiol Cell Physiol, 330, C943 - C953
Models of the human heart for biomedical research: Opportunities and challenges.
Journal article
Streckfuss-Bömeke K. et al, (2026), Physiol Rep, 14

