Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The Srinivas Group's paper "Mechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assay" has been published in PNAS.

Blastocyst hatching is crucial for successful implantation of mammalian embryos and a common failure point during IVF.

They have developed a technique to measure blastocyst pressure, enabling them to quantify physiological parameters and provide additional measures of efficiency in IVF optimization.

The technique reveals that mechanical stretching of the zona by the blastocyst is essential for efficient hatching.

The full article can be viewed here.

Similar stories

Randy Bruno and Scott Waddell receive Wellcome Discovery Awards

Congratulations are in order for Professors Randy Bruno and Scott Waddell who have each been awarded a prestigious Wellcome Trust Discovery Award to significantly enhance our understanding of higher cognitive functions.

Researchers discover novel form of adaptation in the auditory system

DPAG’s auditory neuroscience researchers have found that the auditory system adapts to the changing acoustics of reverberant environments by temporally shifting the inhibitory tuning of cortical neurons to remove reverberation.

Collaborative team driven by DPAG and Chemistry awarded RSC Horizon Prize

The Molecular Flow Sensor Team, with collaborating members principally from DPAG’s Robbins and Talbot groups and the Department of Chemistry, has been named the winner of the Royal Society of Chemistry’s (RSC) Analytical Division Horizon Prize for the development of a new technology for measuring lung function.

REF 2021 results

Oxford Parkinson’s Disease Centre awarded £3.8 million to reveal the role of calcium in Parkinson’s

A collaborative research team led by the Oxford Parkinson’s Disease Centre (OPDC) has been awarded a £3.8 million Wellcome Trust Collaborative Award to study the function of calcium in dopamine neurons, and how this is plays a role in Parkinson’s. Their research will help explain how and why dopamine neurons are vulnerable in the disease and look at how they may be preserved.