17 May 2021
A new study from the Lakhal-Littleton Group has addressed a long-standing gap in our understanding of systemic iron homeostasis. It provides the first formal demonstration that the hormone hepcidin controls iron reabsorption in the kidney, in a manner that impacts the body’s iron levels, under normal physiological conditions. It also demonstrates for the first time how this mechanism becomes critically important in the development of iron disorders.
7 April 2021
The post is in association with a Tutorial Fellowship at Brasenose College.
27 October 2020
Congratulations are in order for Associate Professor Samira Lakhal-Littleton, who has been awarded a Senior Non-Clinical Fellowship by the Medical Research Council to further her lab's work exploring the implications of the cardiac hepcidin/ferroportin axis for the management of iron deficiency in heart failure.
18 June 2020
A key hormone in the fetal liver has been found for the first time to play a critical role in determining iron endowment in the newborn baby. Up until now, widely held notions made in comparison to how the adult liver controls iron in the body have led to a common focus on how maternal iron status and function of the placenta determines a baby's iron status. A new study from the Lakhal-Littleton group reveals a more autonomous process takes place within the fetus than previously understood.
18 June 2020
The annual Prize Lecture from The Physiological Society will provide an opportunity to highlight the importance of the Lakhal-Littleton lab's work into iron control in systems physiology.
3 June 2019
A new discovery from the Lakhal-Littleton Group on how iron deficiency affects the vasculature of the lung could hold the key to improving treatment of pulmonary arterial hypertension.
28 May 2019
Congratulations are in order to Associate Professor Samira Lakhal-Littleton on her election to a major international organisation dedicated to advancing our understanding of the role of iron in biology and medicine.
24 May 2019
DPAG sponsored a hit "Our Body" night for Pint of Science 2019 with well received talks from Prof Ana Domingos and Prof Samira Lakhal-Littleton.