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New review reveals proof of concept for an anti-obesity immunotherapy
2 July 2021
The Domingos lab has published a new opinion piece in Science investigating the implications of a Memorial Sloan Kettering Cancer Center study that lays the foundations for a potential new anti-obesity treatment in the form of targeting adipose tissue-resident macrophages.
New pathway established for multisensory cortical communication
28 June 2021
Integration of information across the senses is critical for perception. This activity is thought to arise primarily from connections made in the brain's sensory cortical areas. A new paper from the King Group uncovers evidence for the first time on the little understood role of subcortical circuits in shaping the multisensory properties of primary cortical neurons.
Gero Miesenböck FRS gives the 2021 Sherrington Prize Lecture ahead of Sherrington Plaque unveiling
24 June 2021
The Department's most prestigious named lecture was delivered this year by Shaw Prize winner and Waynflete Professor of Physiology Gero Miesenböck FRS in honour of our 1913 Waynflete Professor and Nobel Laureate Sir Charles Sherrington OM GBE PRS. The lecture was followed by the unveiling of The Physiological Society blue plaque honouring Sherrington by Sir Colin Blakemore FRS.
Diversifying the Sherrington building walls
22 June 2021
This week framed photographs of 16 women who have contributed to the success of DPAG were displayed on the main stairwell of the Sherrington Building as part of our 2021 Centenary project.
Sherrington Talks 2021 Prize Winners
21 June 2021
The 2021 Sherrington talks were presented by graduate students in their third year of DPhil research study.
Iron deficiency anaemia in early pregnancy increases risk of heart defects, suggests new research
8 June 2021
In animal models, iron deficient mothers have a greatly increased risk of having offspring with congenital heart disease (CHD). The risk of CHD can be greatly reduced if the mother is given iron supplements very early in pregnancy. Additionally, embryos from a mouse model of Down Syndrome were particularly vulnerable to the effects of maternal iron deficiency, leading to a higher risk of developing severe heart defects.
Nicola Smart to deliver John French Lecture
2 June 2021
The British Atherosclerosis Society's John French Memorial Lecture is named in honour of the Oxford-based pathologist, Dr John French, who made seminal observations and contributions to the field of cardiovascular pathology.
Celebrating the Women of DPAG
1 June 2021
To mark the centenary of women being awarded degrees at Oxford University, DPAG celebrates some of the women who have contributed to the success of the Department, and its predecessor departments, over the last century
The only way is UPP!
19 May 2021
The OPDC is delighted to announce that Parkinson’s UK have agreed to fund a further four and a half years of ODPC Discovery Cohort follow-up from August 2021.
New target to develop immunosuppressants
18 May 2021
A new study from the Parekh Group has resolved a long-standing question in our understanding of intracellular Ca2+ signalling, namely how a specific type of Ca2+ channel is uniquely able to signal to the nucleus to regulate gene expression. By unravelling this mechanism, researchers have identified a new approach for developing immunosuppressant drugs.
How the kidney contributes to healthy iron levels and disease
17 May 2021
A new study from the Lakhal-Littleton Group has addressed a long-standing gap in our understanding of systemic iron homeostasis. It provides the first formal demonstration that the hormone hepcidin controls iron reabsorption in the kidney, in a manner that impacts the body’s iron levels, under normal physiological conditions. It also demonstrates for the first time how this mechanism becomes critically important in the development of iron disorders.
Scott Waddell honoured by the Academy of Medical Sciences
12 May 2021
Congratulations are in order to Professor Scott Waddell FMedSci on his election to The Academy of Medical Sciences.
Nchimunya Nelisa Tebeka wins Diabetes UK Early Career Investigator Award
10 May 2021
Congratulations are in order to Rhodes Scholar Nchimunya Nelisa Tebeka, who has been awarded this year's Diabetes UK Early Career Investigator Award for her DPhil work. This award is awarded for the best basic or clinical science oral abstract presentation at the Diabetes UK Professional Conference.
New research to radically alter our understanding of synaptic development
14 April 2021
A new study from the Molnár group on the role of regulated synaptic vesicular release in specialised synapse formation has made it to the cover of Cerebral Cortex.
Samira Lakhal-Littleton appointed Associate Professor in Cell Physiology
7 April 2021
The post is in association with a Tutorial Fellowship at Brasenose College.
Being "in the zone": how waking activity controls sleep need
7 April 2021
A new study from the Vyazovskiy group suggests that how and where we spend our time while awake impacts how much we need to sleep - it does not only depend on how long we are awake.
Gero Miesenböck to deliver The Physiological Society's Annual Review Prize Lecture
6 April 2021
The Annual Review Prize Lecture is The Physiological Society's most prestigious lecture.
New target identified to develop treatment for Abdominal Aortic Aneurysm
30 March 2021
A new study from the Smart group has shed light on a key regulatory step in the initiation and progression of Abdominal Aortic Aneurysm by revealing the protective role of a previously little known small protein.
New research grant to Pawel Swietach to further understanding of propionic acidemia
26 March 2021
A new collaborative project led by the Swietach group funded by the Propionic Acidemia Foundation will investigate the disease mechanisms and risk factors for cardiac disease caused by a severe inherited disorder.
Physiology drawings enhance our understanding of the 'Amazing Body'
24 March 2021
Visiting academic Dr Lizzie Burns received an outreach grant from The Physiological Society to create a novel set of engaging drawings for adult colouring-in to learn about our remarkable human body. Dr Burns has collaborated with members of The Society, including DPAG's Heidi de Wet, Peter Robbins, Keith Dorrington and Andrew King, to illustrate a wide range of physiological topics.