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Prof. Dr. Nils Brose honours former teacher Marianne Fillenz in Memorial Lecture
5 March 2020
The annual lecture is held in honour of one of the great physiologists of the last century, Marianne Fillenz. Fillenz was a devoted and much loved University Demonstrator in the Laboratory of Physiology and her lab was positioned at the forefront of the application of measuring chemicals that could be detected directly at the electrode.
Oxford Medical Students and DPAG tutors are setting the standard for neuroanatomy teaching
5 March 2020
Pre-clinical Medicine Undergraduate students Kacper Kurzyp, Rafee Ahmed and Oliver Bredemeyer achieved Oxford University's best ever performance in The National Undergraduate Neuroanatomy Competition at the University of Southampton. Their participation was sponsored by DPAG with Professor Zoltán Molnár and Departmental Lecturer Dr Michael Gilder providing extra tuition to prepare them for their successful performances.
Communicating the messages of extracellular vesicles to the wider public
2 March 2020
DPAG's Denis Noble has collaborated with Wood Group researchers in the Department of Paediatrics to produce innovative podcast talks on a prominent global platform, the Future Tech Podcast, following the successful DPAG hosted fourth annual Oxosome meeting. Following the release of the final podcast talk in February 2020, today we chart the story leading to these innovative pieces of public engagement.
Professor Eve Marder delivers the 2020 Mabel FitzGerald Prize Lecture
24 February 2020
The annual lecture is held in honour of the pioneering physiologist and clinical pathologist, Mabel Purefoy FitzGerald.
New human heart model set to boost future cardiac research and therapies
31 January 2020
DPAG's Dr Jakub Tomek and Professor Blanca Rodriguez's Computational Cardiovascular Science Team have developed a new computer model that recreates the electrical activity of the ventricles in a human heart. In doing so, they have uncovered and resolved theoretical inconsistencies that have been present in almost all models of the heart from the last 25 years and created a new human heart model that could enable more basic, translational and clinical research into a range of heart diseases and potentially accelerate the development of new therapies.
New target identified for repairing the heart after heart attack
30 January 2020
An immune cell is shown for the first time to be involved in creating the scar that repairs the heart after damage. The Riley Group study was funded by the British Heart Foundation and led by BHF CRE Intermediate Transition Research Fellow Dr Filipa Simões.
New insights into how the brain makes sense of our constantly changing soundscape
16 January 2020
We experience a wide range of sounds at varying levels. The brain's auditory neurons constantly adapt their responses to changes in sound level to help us perceive and understand what we hear. King Group researchers have previously demonstrated how these neurons do this and have now produced new evidence for exactly where this happens in the brain and the perceptual consequences of these adaptations.
Malnutrition linked with increased risk of Zika birth defects
15 January 2020
The severity of Zika virus-related deformations in babies has been shown to be affected by environmental factors such as maternal nutrition. The study was partially funded by a joint MRC Grant between DPAG's Professor Zoltán Molnár and Associate Professor Patricia Garcez of the Federal University of Rio de Janeiro.
Understanding the mechanisms driving a major type of immune cell to keep our gut healthy
10 January 2020
A news and views article published in Nature Immunology by Domingos Group researchers examines significant recent research revealing how group 3 innate lymphoid cells (ILC3s), the cells responsible for protecting the gut and maintaining intestinal homeostasis, are regulated. In doing so, they also reveal important new research avenues of ILCs activation in the body.
New target identified to help prevent dangerous heart rhythms after heart attack
8 January 2020
For many years, we have been using beta-blockers to neutralise a specific stress hormone and prevent dangerous heart rhythms following a heart attack. However, a new study led by Associate Professor Neil Herring and published in the European Heart Journal has uncovered evidence for an additional stress hormone acting as a key trigger for dangerous heart rhythms that is not currently targeted by these drugs.
Biomarker predicts which patients with heart failure have a higher risk of dying
7 January 2020
UCLA Researchers in collaboration with DPAG researchers from the Paterson and Herring Groups have identified a biomarker for increased risk of early mortality in patients with heart failure. Associate Professor Neil Herring is senior author.
Prof Robin Klemm is joining DPAG this summer
6 January 2020
Prof Robin Klemm will be joining our department in June 2020 as the Associate Professor of Physiological Metabolism. Research in the Klemm lab focuses primarily on understanding the molecular cell biology of professional fat storing cells called white adipocytes.
Heidi de Wet answers the Big Question: Why do diets fail?
3 January 2020
It's a new year (and a new decade!) and many of us will be looking to turn over a new leaf when it comes to diet and lifestyle. But - as anyone who's tried one will know - diets are very difficult to stick to. In a new episode of the Big Questions podcast, Associate Professor Heidi de Wet answers "Why do diets fail?". She also provides some great tips for a healthier lifestyle along the way!
How the brain learns from making difficult decisions
19 December 2019
A new study led by Dr Armin Lak suggests that we learn best when we make decisions outside of our comfort zone, and sheds light on how the brain might achieve this.