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An in-depth look into a collaborative DPAG, Chemistry and Oxford Martin School project pioneering a radical new approach in which the brain is repaired with 3D-printed neural tissues.
Neuroscience
We host a number of internationally recognised neuroscience groups, with expertise in a wide range of experimental and computational methods.
Metabolism & Endocrinology
We use the full range of modern molecular genetic and imaging techniques to study a range of metabolic areas.
Functional Genomics
We play a leading role in the development of more efficient and cost-effective sequencing technologies.
Development & Cell Biology
We dissect the molecular and cellular mechanisms underlying a range of developmental and reproductive processes.
Cell Physiology
We study everything from the structure of ion channels and transporters right up to their role in behaviour and human disease.
Cardiac Sciences
We are recognised internationally for our pioneering approaches to systems biology and to computational modelling of the heart.
Interviewees
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Zoltan Molnar
Professor of Developmental Neuroscience
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Francis Szele
Associate Professor of Developmental Biology
Project Collaborators
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Professor of Chemical Biology |
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Oxford Martin Fellow |
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Funder
Related Images
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Human brain progenitor cells differentiate into neurons and astrocytes 13 days after 3D printing. Adapted from Zhou et al., Advanced Materials, June 2020 |
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Layer 6 (green) and layer 5 (red) of the cortex of a Pax 6 mutant mouse cerebral cortex. Adapted from Tuoc et al., Journal of Neuroscience, July 2009 |
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Clonally-related cells labelled in a chick brai. Adapted from García-Moreno et al., Development, April 2014 |
Related Publications
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New insights into the development of the human cerebral cortex.
Journal article
Molnár Z. et al, (2019), J Anat, 235, 432 - 451
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High-Resolution Patterned Cellular Constructs by Droplet-Based 3D Printing.
Journal article
Graham AD. et al, (2017), Sci Rep, 7
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Sip1 downstream Effector ninein controls neocortical axonal growth, ipsilateral branching, and microtubule growth and stability.
Journal article
Srivatsa S. et al, (2015), Neuron, 85, 998 - 1012
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CLoNe is a new method to target single progenitors and study their progeny in mouse and chick.
Journal article
García-Moreno F. et al, (2014), Development, 141, 1589 - 1598
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Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice.
Journal article
Tuoc TC. et al, (2009), J Neurosci, 29, 8335 - 8349
Bayley H. et al, (2020), Advanced Materials
A Tissue-Like Printed Material