4 July 2022
The Annual Review Prize Lecture is The Physiological Society's most prestigious lecture.
7 June 2022
The Molecular Flow Sensor Team, with collaborating members principally from DPAG’s Robbins and Talbot groups and the Department of Chemistry, has been named the winner of the Royal Society of Chemistry’s (RSC) Analytical Division Horizon Prize for the development of a new technology for measuring lung function.
5 May 2022
DPAG scientists across four research groups were highlighted at the major annual European Society of Cardiology basic science conference (FCVB 2022). Congratulations are in order for Dr KC Park on receiving the Young Investigator Award and to Dr Elisabetta Gamen on winning the Moderated Poster Prize.
13 April 2022
Research led by Dr Alzbeta Hulikova and Professor Pawel Swietach has, for the first time, described the potential regulation of nuclear acid-base chemistry in neonatal and adult cardiomyocytes, and explained its relevance in the context of heart physiology and pathology.
7 April 2022
A new Klemm Lab-led paper has uncovered a new mechanism involving the endoplasmic reticulum that is critical to the organisation and position of the microtubule (MT) cytoskeleton, which ultimately dictates the shape and function of our body’s cells.
25 March 2022
A new Novo Nordisk project paper has uncovered the role of ACC1 enzyme in the regulation of glucagon secretion for the first time. This raises the prospect of a potential new therapeutic target in the context of type 2 diabetes and metabolic disorders characterised by hyperglycaemia.
21 March 2022
Congratulations are in order to Professor Pawel Swietach, who will represent the Department in strategic decision-making for Oxford Cancer.
11 March 2022
A new paper led by Dr Johanna Michl and Professor Pawel Swietach from DPAG’s Swietach Group has identified a new gene that allows cancer cells to survive in the typically acidic microenvironment of a malignant tumour. They have discovered drugs that inhibit the gene in other medical conditions also selectively kill cancer cells at acidic pH, without damaging healthy tissue. This defines a novel strategy for targeting acidic tumour regions.
13 September 2021
New research from the Swietach Group in collaboration with NHS Blood and Transplant has demonstrated that the process of storing blood in blood banks can negatively impact the function of red blood cells and consequently may reduce the effectiveness of blood transfusions, a treatment commonly used to combat anaemia.
3 September 2021
New research from the Parekh and Zaccolo groups reveals that a prototypical anchoring protein, known to be responsible for regulating several important physiological processes, also orchestrates the formation of two important universal second messengers.
18 May 2021
A new study from the Parekh Group has resolved a long-standing question in our understanding of intracellular Ca2+ signalling, namely how a specific type of Ca2+ channel is uniquely able to signal to the nucleus to regulate gene expression. By unravelling this mechanism, researchers have identified a new approach for developing immunosuppressant drugs.
10 May 2021
Congratulations are in order to Rhodes Scholar Nchimunya Nelisa Tebeka, who has been awarded this year's Diabetes UK Early Career Investigator Award for her DPhil work. This award is awarded for the best basic or clinical science oral abstract presentation at the Diabetes UK Professional Conference.
10 February 2021
A clinical trial has commenced this week to test whether a drug called almitrine can help people who are seriously ill with COVID-19 to recover from the disease.
30 October 2020
Congratulations are in order to Pawel Swietach on his conferral of the title of full Professor. Research in the Swietach Lab is driven by an interest in how biological processes are affected by chemical acidity.
21 October 2020
The Zaccolo Group has identified a new mechanism that regulates mitochondria quality control, a process that is crucial to maintaining healthy cells and preventing disease.
1 September 2020
Collaborative research from a leading US cancer centre and the Swietach Group has found that Low pH in lymph nodes inhibits effector T cells, while still allowing T cell activation.
20 July 2020
DPAG is among the departments receiving funding from the University's research response fund to undertake COVID-19 research. As part of this effort, the Swietach lab has been studying oxygen transport in the blood of COVID-19 patients. The first results of this study are now published in the British Journal of Haematology and could pave the way for new guidelines for treating the virus.
12 June 2020
The destruction of red blood cells known as hemolysis in the newborn baby is very dangerous, but existing clinical methods are not sufficient for rapid diagnosis and can lead to delays early-life care. A new Swietach Group paper has identified a biomarker that could significantly speed up the process.
8 June 2020
Professor Anant Parekh is to deliver the Public Lecture at the prestigious annual conference due to be held in Pune, India, in January 2021.
29 May 2020
Researchers at the University of Oxford led by DPAG's Professor Peter Robbins are working with clinical collaborators from NHS hospitals to carry out a new clinical drug trial aimed at treating COVID-19, funded by LifeArc. It will test a drug that could raise oxygen levels in the blood in COVID-19 patients in order to improve their chances of recovery. Raising oxygen levels is important in COVID-19, because many patients with the disease die when oxygen levels in their arterial blood fall to levels that are too low to support life.