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The Wade-Martins Group has identified how the dysfunction of a key protein, LRRK2, causes the neurons affected in Parkinson's to lose their ability to effectively clear out cell components that have been damaged. This discovery has enabled the team to find a new way to target and correct this issue, paving the way for a potential new clinical treatment.
Neuroscience
We host a number of internationally recognised neuroscience groups, with expertise in a wide range of experimental and computational methods.
Metabolism & Endocrinology
We use the full range of modern molecular genetic and imaging techniques to study a range of metabolic areas.
Functional Genomics
We play a leading role in the development of more efficient and cost-effective sequencing technologies.
Development & Cell Biology
We dissect the molecular and cellular mechanisms underlying a range of developmental and reproductive processes.
Cell Physiology
We study everything from the structure of ion channels and transporters right up to their role in behaviour and human disease.
Cardiac Sciences
We are recognised internationally for our pioneering approaches to systems biology and to computational modelling of the heart.