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Professor Zoltán Molnár has been awarded an Einstein Visiting Fellowship to Charité - University Medicine, Berlin. This award sees him join the dynamic Oxford | Berlin collaboration, a strategic research partnership that supports high quality joint research initiatives across all disciplines of its member institutions, of which Neuroscience is a major focus.

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Drug trial that could improve respiratory recovery from COVID-19 now underway

10 February 2021

A clinical trial has commenced this week to test whether a drug called almitrine can help people who are seriously ill with COVID-19 to recover from the disease.

Same genome, different worlds: How a similar brain causes sexually dimorphic behaviours

27 January 2021

A new paper from the Goodwin group based in DPAG's Centre for Neural Circuits and Behaviour has shown how males and females are programmed differently in terms of sex.

New form of gift wrap drives male reproductive success

26 January 2021

The transfer of complex mixtures of signals and nutrients between individuals is a key step in several biologically important events in our lives, such as breastfeeding and sexual intercourse. However, we know relatively little about the ways in which the molecular gifts involved are packaged to ensure their successful delivery to the recipient.

Just over half of British Indians would take COVID vaccine

21 January 2021

University of Oxford researchers from the Department of Physiology, Anatomy and Genetics (DPAG) and the Department of Psychiatry, in collaboration with The 1928 Institute, have published a major new study on the impact of COVID-19 on the UK’s largest BME population.

Earliest origins of the forming heart identified

8 January 2021

The earliest known progenitor of the outermost layer of the heart has been characterised for the first time and linked to the development of other critical cell types in the developing heart in a new paper from the Srinivas group led by BHF Immediate Fellow Dr Richard Tyser.

Covid-19 lung damage identified in study

2 December 2020

In a new study into the longer-term damage amongst patients recovering from COVID-19, DPAG Research Fellow Dr James Grist of the Tyler Lab has been running a novel scanning technique that shows a dramatic decrease in the ability of the lungs to diffuse gas in to the blood stream after COVID infection. This work may shed light on the problem of breathlessness after COVID infection and help guide us in understanding therapeutic selection and efficacy.

A clue to how a memory-enhancing pill might work

27 November 2020

Hundreds of dietary supplements have been reported to improve cognitive and emotional function in humans, but few have scientific foundation. A new study from the Waddell group provides fresh insight into how dietary Magnesium supplementation can influence memory performance.

New MRI technique could detect early signs of heart failure in cancer patients following chemotherapy

19 November 2020

New research led by Oxford BHF CRE Intermediate Transition Fellow Dr Kerstin Timm shows that a recently developed imaging technique pioneered by the Tyler Group can detect early metabolic changes in the heart caused by a commonly used chemotherapy drug, which is known to increase risk of heart failure in cancer survivors.

Researchers reveal surprising simplicity behind our ability to hear

26 October 2020

A computational modelling study from the King Group demonstrates that the way sounds are transformed from the ear to the brain’s auditory cortex may be simpler than expected. These findings not only highlight the value of computational modelling for determining the principles underlying neural processing, but could also be useful for improving treatments for patients with hearing loss.

New insights into mitochondria quality control could hold the key to treating metabolic disorders

21 October 2020

The Zaccolo Group has identified a new mechanism that regulates mitochondria quality control, a process that is crucial to maintaining healthy cells and preventing disease.

‘Junk’ DNA could be rewiring our brains

16 October 2020

A new study by Waddell Group Neuroscientists at the Centre for Neural Circuits and Behaviour shows that mobile genetic elements that were active in the genomes of our ancestors could be closely linked to important functions in our brain and might help diversify our behaviour, cognition and emotions.

The transient blueprint of the brain

16 October 2020

Transient neurones match the spontaneous and sensory driven activities to shape cortical circuits: a landmark collaborative review published in Science from Professor Zoltán Molnár, Professor Patrick Kanold and Professor Heiko Luhmann.

Sites of early dysfunction in Parkinson's identified

2 October 2020

A new collaborative study from the Oxford Parkinson’s Disease Centre led by Prof Stephanie Cragg and Dr Bradley Roberts has revealed that GABA transporters on astrocytes, the brain's lesser known yet critically important cells, support dopamine release and are sites of early dysfunction in parkinsonism.

Tiny brain “tweezers” could hold the key to treat Parkinson’s

28 September 2020

A collaborative study led by the OPDC's Dr Nora Bengoa-Vergniory has shown that compounds known as molecular tweezers could become a promising disease modifying therapy for Parkinson’s.

Einstein Visiting Fellowship awarded to Zoltán Molnár

24 September 2020

Recharging the battery of the diabetic heart

4 September 2020

A new paper from the Heather and Tyler groups has uncovered the mechanism responsible for reduced energy in the hearts of patients with type 2 diabetes and revealed a new therapeutic strategy to reverse the energy deficit.

Acidic niche keeps lymphatic system in check during immune response

1 September 2020

Collaborative research from a leading US cancer centre and the Swietach Group has found that Low pH in lymph nodes inhibits effector T cells, while still allowing T cell activation.

Genetic study points to cells responsible for Parkinson’s

25 August 2020

New results from a collaborative Oxford Parkinson’s Disease Centre and Cardiff University study on the cellular origins of Parkinson's could be key to developing new treatments.

How brain networks cooperate to control our sleep

13 August 2020

Two new papers from the Vyazovskiy Group and both Oxford University and international collaborators have made important progress in bridging the gap between the local and global levels of sleep regulation.

The ethical cost of doing nothing

7 August 2020

In the wake of concern raised about the ethics and risks of performing genetic interventions in macaque monkeys to study models of human neuropsychiatric conditions, Professor Andrew Parker analyses how decision makers evaluate these situations and highlights the ethical consequences if research is not carried out.

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