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Thousands of genes are involved in the regulation of our day-to-day metabolism and relatively little is understood about their function. One key protein, an ABC Transporter called ABCC5, has recently been predicted to be a susceptibility gene for Type 2 diabetes. In a new study selected as Editor's Choice in Obesity, Associate Professor Heidi de Wet has confirmed ABCC5's role in energy metabolism and identified the mechanism behind its metabolic impact for the first time.

Rare gut endocrine cells visualised using green fluorescence (left) and electron microscopy (right)

Manuela Zaccolo

MD, PhD, FRSB Manuela Zaccolo - Deputy Head of Department

Akinola Akinbote

PhD Akinola Akinbote - Postdoctoral Research Scientist

Konstantinos Pataridis

Konstantinos Pataridis - Postdoctoral Research Scientist

Manil Bradai

Manil Bradai - Research Assistant

Karina Piotrowska

Karina Piotrowska - DPhil researcher

Hannah Bailey

PhD Hannah Bailey - Postdoctoral Research Scientist

Keith Buckler

Keith Buckler - Emeritus Associate Professor of Physiology

Liam Cocker

Liam Cocker - Research Assistant

Catherine King

Catherine King - DPhil Student

Maryam Yasaminshirazi

Maryam Yasaminshirazi - Lab Manager

Richard Wade-Martins

MA, DPhil Richard Wade-Martins - Professor of Molecular Neuroscience

Jacinta Kalisch-Smith

PhD Jacinta Kalisch-Smith - BHF Intermediate Basic Science Fellow

Stephanie Cragg

MA DPhil MAE Stephanie Cragg - Professor of Neuroscience

Yufei Cao

Samira Lakhal-Littleton

BSc DPhil FESC MAE Samira Lakhal-Littleton - MRC Senior Non-Clinical Research Fellow, Principal Investigator, Professor of Cell Physiology and Tutorial Fellow in Medicine