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Search results (8)

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Genetically encoded and modular subcellular organelle probes reveal dysfunction in lysosomes and mitochondria driven by PRKN knockout.

Goldman C. et al, (2025), iScience, 28

Genetically Encoded and Modular SubCellular Organelle Probes (GEM-SCOPe) reveal lysosomal and mitochondrial dysfunction driven by PRKN knockout.

Goldman C. et al, (2025), bioRxiv

Cholesterol-mediated Lysosomal Dysfunction in APOE4 Astrocytes Promotes α-Synuclein Pathology in Human Brain Tissue.

Mesentier-Louro LA. et al, (2025), bioRxiv

Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model.

Morrone Parfitt G. et al, (2024), Nat Commun, 15

Reconstruction of the Blood-Brain Barrier In Vitro to Model and Therapeutically Target Neurological Disease.

Goldman C. et al, (2023), J Vis Exp

Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity.

Sarrafha L. et al, (2023), iScience, 26

High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells.

Sarrafha L. et al, (2021), STAR Protoc, 2

Proteasome β5 subunit overexpression improves proteostasis during aging and extends lifespan in Drosophila melanogaster.

Nguyen NN. et al, (2019), Sci Rep, 9