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Thousands of genes are involved in the regulation of our day-to-day metabolism and relatively little is understood about their function. One key protein, an ABC Transporter called ABCC5, has recently been predicted to be a susceptibility gene for Type 2 diabetes. In a new study selected as Editor's Choice in Obesity, Associate Professor Heidi de Wet has confirmed ABCC5's role in energy metabolism and identified the mechanism behind its metabolic impact for the first time.
Long-overlooked cerebral cortical cell layer may hold key to attention
2 February 2026
Berlin and Oxford collaborative researchers funded by Einstein Foundation propose a new circuit theory linking a little-known cortical layer to attention and brain disorders.
Why do we need sleep? Oxford researchers find the answer may lie in mitochondria
16 July 2025
A New study uncovers how a metabolic “overload” in specialised brain cells triggers the need to sleep. Sleep may not just be rest for the mind - it may be essential maintenance for the body’s power supply.

