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Search results (208)

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Dopamine release from Parkinson’s patient-derived neurons is disrupted due to impaired synaptic vesicle loading

Cramb KML. et al, (2026)

SARM1 activation induces reversible mitochondrial dysfunction and can be prevented in human neurons by antisense oligonucleotides.

Loreto A. et al, (2025), Neurobiol Dis, 213

Recent developments in gene therapy for Parkinson's disease.

Szunyogh S. et al, (2025), Mol Ther, 33, 2052 - 2064

Tau depletion in human neurons mitigates Aβ-driven toxicity.

Ng B. et al, (2024), Mol Psychiatry, 29, 2009 - 2020

A fluid-walled microfluidic platform for human neuron microcircuits and directed axotomy.

Nebuloni F. et al, (2024), Lab Chip, 24, 3252 - 3264

Early deficits in an in vitro striatal microcircuit model carrying the Parkinson's GBA-N370S mutation.

Do QB. et al, (2024), NPJ Parkinsons Dis, 10

Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease.

Kilfeather P. et al, (2024), Cell Rep, 43

Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's.

Brimblecombe KR. et al, (2024), Eur J Neurosci, 59, 1242 - 1259

Multi-modal proteomic characterization of lysosomal function and proteostasis in progranulin-deficient neurons.

Hasan S. et al, (2023), Mol Neurodegener, 18

A fluid-walled microfluidic platform for human neuron microcircuits and directed axotomy

Nebuloni F. et al, (2023)

C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9.

Vahsen BF. et al, (2023), Nat Commun, 14

Patient-derived iPSC models of Friedreich ataxia: a new frontier for understanding disease mechanisms and therapeutic application.

Maheshwari S. et al, (2023), Transl Neurodegener, 12

Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson's disease models.

Williamson MG. et al, (2023), Hum Mol Genet, 32, 2808 - 2821

Impaired dopamine release in Parkinson's disease.

Cramb KML. et al, (2023), Brain, 146, 3117 - 3132

Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson's iPSC-dopamine neurons.

Beccano-Kelly DA. et al, (2023), iScience, 26

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