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Search results (16)

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Hydralazine inhibits cysteamine dioxygenase to treat preeclampsia and senesce glioblastoma.

Shishikura K. et al, (2025), Sci Adv, 11

Making sense of oxygen sensing.

Ratcliffe PJ. and Keeley TP., (2025), EMBO J, 44, 4661 - 4665

Nitric oxide promotes cysteine N-degron proteolysis through control of oxygen availability.

Kim H. et al, (2025), Proc Natl Acad Sci U S A, 122

Hif-2α programs oxygen chemosensitivity in chromaffin cells.

Prange-Barczynska M. et al, (2024), J Clin Invest, 134

N-terminal cysteine acetylation and oxidation patterns may define protein stability.

Heathcote KC. et al, (2024), Nat Commun, 15

Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells.

Tian Y-M. et al, (2023), J Biol Chem, 299

Monitoring ADO dependent proteolysis in cells using fluorescent reporter proteins.

Smith E. and Keeley TP., (2023), 686, 267 - 295

Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels.

Sevimli G. et al, (2022), Redox Biol, 53

The developmental role of PHD2 in the pathogenesis of pseudohypoxic PPGLs

Prange-Barczynska M. et al, (2022), ACTA PHYSIOLOGICA, 236, 25 - 25

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells.

Wing PAC. et al, (2021), Cell Rep, 35

Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation.

Warpsinski G. et al, (2020), Redox Biol, 37

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants.

Masson N. et al, (2019), Science, 365, 65 - 69

Defining Physiological Normoxia for Improved Translation of Cell Physiology to Animal Models and Humans.

Keeley TP. and Mann GE., (2019), Physiol Rev, 99, 161 - 234

Reduced SERCA activity underlies dysregulation of Ca2+ homeostasis under atmospheric O2 levels.

Keeley TP. et al, (2018), FASEB J, 32, 2531 - 2538

PP2A-mediated feedback mechanism controls Ca2+-dependent NO synthesis under physiological oxygen.

Keeley TP. et al, (2017), FASEB J, 31, 5172 - 5183

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