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Search results (172)

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Phosphodiesterase type 1 regulates adenosine 2A receptor-associated cAMP signaling at the plasma membrane to increase myocardial contractility.

Fitch ML. et al, (2025)

Compartmentalisation in cAMP signalling: A phase separation perspective.

Folkmanaite M. and Zaccolo M., (2025), Br J Pharmacol

GPCR signaling via cAMP nanodomains.

Yadav R. and Zaccolo M., (2025), Biochem J, 482, 519 - 533

Cyclic nucleotide phosphodiesterases as drug targets.

Kelly MP. et al, (2025), Pharmacol Rev, 77

Nanodomain cAMP signaling in cardiac pathophysiology: potential for developing targeted therapeutic interventions.

Zaccolo M. and Kovanich D., (2025), Physiol Rev, 105, 541 - 591

GPCR signalling: Yet another variant route in a highly complex road map.

Demby A. and Zaccolo M., (2024), Cell Calcium, 124

ctivation of IP3R in atrial cardiomyocytes leads to generation of cytosolic cAMP.

Akerman EC. et al, (2024), Am J Physiol Heart Circ Physiol, 327, H830 - H846

Phase separation of protein kinase A: a new paradigm in cardiac regulation?

Folkmanaite M. and Zaccolo M., (2024), Nat Rev Cardiol, 21

G Protein-Coupled Receptor Signaling: New Insights Define Cellular Nanodomains.

Lohse MJ. et al, (2024), Annu Rev Pharmacol Toxicol, 64, 387 - 415

Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation.

Park KC. et al, (2023), Nat Cardiovasc Res, 2, 1221 - 1245

Compartmentalized cAMP signalling and control of cardiac rhythm.

Tomek J. and Zaccolo M., (2023), Philos Trans R Soc Lond B Biol Sci, 378

Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy.

Subramaniam G. et al, (2023), Circ Res, 132, 828 - 848

Using the Proteomics Toolbox to Resolve Topology and Dynamics of Compartmentalized cAMP Signaling.

Kovanich D. et al, (2023), Int J Mol Sci, 24

Regulation of cardiac function by cAMP nanodomains.

Folkmanaite M. and Zaccolo M., (2023), Biosci Rep, 43

cAMP Compartmentalisation in Human Myometrial Cells.

Varley A. et al, (2023), Cells, 12

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