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A new paper from the Heather and Tyler groups has uncovered the mechanism responsible for reduced energy in the hearts of patients with type 2 diabetes and revealed a new therapeutic strategy to reverse the energy deficit.
Injected extracellular vesicles and other nanoparticles hitchhike on erythrocytes and platelets from circulation towards organ clearance
Journal article
Pavlova S. et al, (2026), Extracellular Vesicle, 7
Combined middle meningeal artery embolisation and subdural evacuation port system drainage for chronic subdural haematoma: a systematic review, single-arm meta-analysis, meta-regression, and cost-benefit analysis.
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Nischal SA. et al, (2026), Clin Neurol Neurosurg, 264
Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta-Cell Function.
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Lloyd M. et al, (2026), FASEB J, 40
Cluster-First Labelling: An Automated Pipeline for Segmentation and Morphological Clustering in Histology Whole Slide Images
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Ahmad MH. et al, (2026), arXiv
Generating exosome subtypes: diverse membrane origins and mergers.
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Goberdhan DCI. et al, (2026), Trends Cell Biol
Lamination of primary visual cortex in the macaque: Layer 5 subdivisions.
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Ahmed B. et al, (2026), J Anat
T-World Virtual Human Cardiomyocyte. I. Development, Validation, and Cell Arrhythmogenesis.
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Tomek J. et al, (2026), Circ Res
Organ-Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium.
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Dang QM. et al, (2026), Adv Sci (Weinh)
Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles.
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Karabova MK. et al, (2026), Alzheimers Dement, 22
Presynaptic dopaminergic imaging as a neurodegeneration staging biomarker in the alpha-synucleinopathy continuum.
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Arnaldi D. et al, (2026), Eur J Nucl Med Mol Imaging
Era of Sugammadex: A Paradigm Shift in Airway Management.
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Hagberg CA. et al, (2026), Anesthesiology, 144, 978 - 997
Interstitial cells and arrhythmia.
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Rog-Zielinska EA. et al, (2026), Am J Physiol Cell Physiol, 330, C943 - C953
Auditory Salience Detection Across Wake and Sleep States: Mismatch Negativity and Event-Related Spectral Perturbation in the Rat Superior Colliculus.
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Hasan Nia Roshan J. et al, (2026), J Sleep Res, 35
Serum p-tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder.
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Yan S. et al, (2026), Ann Neurol, 99, 912 - 921
The metabolic balancing act between fatty acid and glucose substrate use for optimal myocardial function: key role for membrane substrate transporters.
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Glatz JFC. et al, (2026), Am J Physiol Heart Circ Physiol, 330, H1195 - H1207
Multimodal, device-based therapeutic targeting of the cardiovascular autonomic nervous system.
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Paton JFR. et al, (2026), Nat Rev Cardiol, 23, 255 - 278
Rational discovery of therapeutic PAK1 allosteric activators.
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He Y. et al, (2026), Cell
The Impact of Polyethylene Glycol Lipid Anchors on the Physicochemical Properties, Protein Corona, Function, and Biodistribution of Lipid Nanoparticles.
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Lu C-E. et al, (2026), ACS Nano, 20, 9875 - 9890
Alzheimer's disease pathology degrades an NMDA receptor-dependent spontaneous activity pattern in cortico-hippocampal circuits.
Journal article
Ellingford R. et al, (2026), Neuron