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A new collaborative drug discovery project in Friedreich’s Ataxia (FA) between the University of Oxford, Ataxia UK, Pfizer Inc, UCL and Imperial College London was recently announced.
Injected extracellular vesicles and other nanoparticles hitchhike on erythrocytes and platelets from circulation towards organ clearance
Journal article
Pavlova S. et al, (2026), Extracellular Vesicle, 7
Combined middle meningeal artery embolisation and subdural evacuation port system drainage for chronic subdural haematoma: a systematic review, single-arm meta-analysis, meta-regression, and cost-benefit analysis.
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Nischal SA. et al, (2026), Clin Neurol Neurosurg, 264
Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta-Cell Function.
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Lloyd M. et al, (2026), FASEB J, 40
Somatic mosaicism in ALS and FTD identifies focal mutations associated with widespread degeneration.
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Zhou Z. et al, (2026), Nat Genet
Cluster-First Labelling: An Automated Pipeline for Segmentation and Morphological Clustering in Histology Whole Slide Images
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Ahmad MH. et al, (2026), arXiv
Generating exosome subtypes: diverse membrane origins and mergers.
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Goberdhan DCI. et al, (2026), Trends Cell Biol
Lamination of primary visual cortex in the macaque: Layer 5 subdivisions.
Journal article
Ahmed B. et al, (2026), J Anat
T-World Virtual Human Cardiomyocyte. II. Organ-Scale Simulations and Applications.
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Tomek J. et al, (2026), Circ Res
T-World Virtual Human Cardiomyocyte. I. Development, Validation, and Cell Arrhythmogenesis.
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Tomek J. et al, (2026), Circ Res
Organ-Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium.
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Dang QM. et al, (2026), Adv Sci (Weinh)
Era of Sugammadex: A Paradigm Shift in Airway Management.
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Hagberg CA. et al, (2026), Anesthesiology, 144, 978 - 997
Models of the human heart for biomedical research: Opportunities and challenges.
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Streckfuss-Bömeke K. et al, (2026), Physiol Rep, 14
Presynaptic dopaminergic imaging as a neurodegeneration staging biomarker in the alpha-synucleinopathy continuum.
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Arnaldi D. et al, (2026), Eur J Nucl Med Mol Imaging
Multimodal, device-based therapeutic targeting of the cardiovascular autonomic nervous system.
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Paton JFR. et al, (2026), Nat Rev Cardiol, 23, 255 - 278
Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles.
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Karabova MK. et al, (2026), Alzheimers Dement, 22
Cortical firing dynamics during micro-arousals vary with sleep/wake history and micro-arousal duration.
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Hauglund NL. et al, (2026), Sci Rep
The metabolic balancing act between fatty acid and glucose substrate use for optimal myocardial function: key role for membrane substrate transporters.
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Glatz JFC. et al, (2026), Am J Physiol Heart Circ Physiol, 330, H1195 - H1207
Interstitial cells and arrhythmia.
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Rog-Zielinska EA. et al, (2026), Am J Physiol Cell Physiol, 330, C943 - C953
Auditory Salience Detection Across Wake and Sleep States: Mismatch Negativity and Event-Related Spectral Perturbation in the Rat Superior Colliculus.
Journal article
Hasan Nia Roshan J. et al, (2026), J Sleep Res, 35