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Enhancer detectors are DNA constructs which, when introduced into a eukaryotic genome, respond to nearby genomic transcriptional regulatory elements by means of a reporter gene, revealing the expression pattern of genes in their vicinity. Recent experiments in Drosophila suggest that enhancer detection is a powerful method to identify genes that are expressed in the nervous system. Since enhancer detectors allow a rapid molecular and genetic characterization of genes in their vicinity, the method will greatly facilitate the study of neural development and behavior.

Original publication

DOI

10.1002/bies.950120502

Type

Journal article

Journal

Bioessays

Publication Date

05/1990

Volume

12

Pages

199 - 204

Keywords

Animals, DNA Transposable Elements, Drosophila melanogaster, Enhancer Elements, Genetic, Gene Expression, Genetic Techniques, Nervous System, Nervous System Physiological Phenomena