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Emerging technologies from optics, genetics, and bioengineering are being combined for studies of intact neural circuits. The rapid progression of such interdisciplinary "optogenetic" approaches has expanded capabilities for optical imaging and genetic targeting of specific cell types. Here we explore key recent advances that unite optical and genetic approaches, focusing on promising techniques that either allow novel studies of neural dynamics and behavior or provide fresh perspectives on classic model systems.

Original publication

DOI

10.1523/JNEUROSCI.3863-06.2006

Type

Journal article

Journal

J Neurosci

Publication Date

11/10/2006

Volume

26

Pages

10380 - 10386

Keywords

Animals, Brain, Gene Targeting, Humans, Microscopy, Fluorescence, Nerve Net, Neural Pathways, Optics and Photonics