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Models of the heart have been developed since 1960, starting with the discovery and modeling of potassium channels. The first models of calcium balance were made in the 1980s and have now reached a high degree of physiological detail. During the 1990s, these cell models were incorporated into anatomically detailed tissue and organ models.

Original publication

DOI

10.1152/physiol.00004.2004

Type

Journal article

Journal

Physiology (Bethesda)

Publication Date

08/2004

Volume

19

Pages

191 - 197

Keywords

Animals, Heart, Heart Diseases, Humans, Models, Cardiovascular, Potassium Channels