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In the current era of functional surgery for movement disorders, deep brain stimulation (DBS) of the globus pallidus internus (GPi) is emerging as the favoured target in the treatment of patients with dystonia. The results of 25 consecutive patients with medically intractable dystonia (12 with generalised dystonia, 7 with spasmodic torticollis, and 6 with other types of dystonia) treated with GPi stimulation are reported. Although comparisons were limited by differences in their respective neurological rating scales, chronic DBS benefited all groups, resulting in clear and progressive improvements in their condition. This study clearly demonstrates that DBS of the GPi provides amelioration of intractable dystonia.

Original publication

DOI

10.1002/mds.10380

Type

Journal article

Journal

Mov Disord

Publication Date

04/2003

Volume

18

Pages

436 - 442

Keywords

Adolescent, Adult, Aged, Botulinum Toxins, Child, Combined Modality Therapy, Dystonia, Electric Stimulation Therapy, Electrodes, Implanted, Female, Follow-Up Studies, Globus Pallidus, Humans, Male, Medical Audit, Middle Aged, Neurologic Examination, Prospective Studies, Torticollis, Treatment Outcome