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The identification of intracellular distributions of noble metal nanoparticles is of great utility for many biomedical applications. We present an effective method to distinguish intracellular from extracellular nanoparticles by selectively quenching the SERS signals from dye molecules adsorbed onto star-shaped gold nanoparticles that have not been internalized by cells.

Original publication

DOI

10.1039/c4nr04687k

Type

Journal article

Journal

Nanoscale

Publication Date

07/11/2014

Volume

6

Pages

12403 - 12407

Keywords

Adsorption, Fluorescent Dyes, Gold, HeLa Cells, Humans, Metal Nanoparticles, Microscopy, Electron, Transmission, Microscopy, Fluorescence, Nanotechnology, Spectrum Analysis, Raman