Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we will assume that you are happy to receive all cookies and you will not see this message again. Click 'Find out more' for information on how to change your cookie settings.

Intra-arterial recordings of potassium concentration ([K+]a) and arterial chemoreceptor discharge were made in six anaesthetized cats while tracheal PO2 was stepped every 2 min (end-tidal PO2 ca. 140, 60, 40 and 95 Torr) at constant PCO2 (33 Torr). [K+]a increased hyperbolically from 3.0 mM to 4.5 mM as arterial PO2 was lowered from 95 to 40 Torr. Because the discharge of arterial chemoreceptors is excited by hyperkalaemia as well as hypoxia, the hypoxic discharge of arterial chemoreceptors may have a component mediated by [K+]a. The mechanisms underlying the arterial K+ increase in hypoxia remain unknown.

Original publication

DOI

10.1113/expphysiol.1988.sp003182

Type

Journal article

Journal

Q J Exp Physiol

Publication Date

07/1988

Volume

73

Pages

623 - 625

Keywords

Action Potentials, Animals, Arteries, Cats, Chemoreceptor Cells, Hypoxia, Potassium