The hypothalamic-pituitary-adrenal axis modulates immunity in response to stress. In a recent report in the May 14, 2020 issue of Nature, Zhang et al. use optogenetic tools to investigate whether the splenic immune response is directly controlled by descending neuronal circuits activated in response to stress.
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Brain, Hypothalamo-Hypophyseal System, Immunity, Humoral, Neurons, Pituitary-Adrenal System