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A new collaborative study from the Oxford Parkinson’s Disease Centre led by Prof Stephanie Cragg and Dr Bradley Roberts has revealed that GABA transporters on astrocytes, the brain's lesser known yet critically important cells, support dopamine release and are sites of early dysfunction in parkinsonism.
Human induced pluripotent stem cell-derived microglia with 1q21.1 deletion and duplication exhibit aberrant inflammatory response
Journal article
Singh T. et al, (2026), Genes and Diseases, 13
Single-cell and spatial transcriptomic analyses of gene therapy-associated retinal inflammation in non-human primates.
Journal article
Sourd C. et al, (2026), Mol Ther Adv, 34
GWAS on short tandem repeats identifies genetic mechanisms in Alzheimer's disease.
Journal article
Gmelin D. et al, (2026), Nat Commun, 17
Nucleophagy removes cytotoxic trapped PARP1.
Journal article
Hoslett G. et al, (2026), Nat Cell Biol
Injected extracellular vesicles and other nanoparticles hitchhike on erythrocytes and platelets from circulation towards organ clearance
Journal article
Pavlova S. et al, (2026), Extracellular Vesicle, 7
Pilot study on virtual reality teaching of the gastrointestinal tract vasculature
Conference paper
Smilevska RS. et al, (2026)
TopoMetry systematically learns and evaluates the latent geometry of single-cell data
Preprint
Oliveira DS. et al, (2026)
2-Triazolylphenols as potent and versatile clicksalicylamide protonophores
Preprint
Ruiz R. et al, (2026)
Epidermal growth factor (EGF) receptor family signalling in cardiomyocyte hypertrophy and heart failure
Preprint
Fuller SJ. et al, (2026)
Wearable Movement-Tracking for Prodromal Parkinson's Disease Detection: A Cross-Country Validation Study.
Journal article
Kahl F. et al, (2026), Mov Disord
Channelrhodopsin Ion Selectivity Determines Mechanisms and Efficacy of Optogenetic Defibrillation in Human Atria and Ventricles
Preprint
Ohnemus S. et al, (2026)
Rethinking hierarchy: the auditory system as an integrated cortical-subcortical network.
Journal article
Lohse M. et al, (2026), Nat Rev Neurosci
Defective regulated secretion: A trigger for Alzheimer's pathology?
Journal article
Verma B. et al, (2026), Prog Neurobiol, 262
Clinical prognostic indicators in multiple system atrophy.
Journal article
Goh YY. et al, (2026), Brain
Synthesis of aryl-fused bicyclo[3.1.1]heptanes and validation as naphthyl bioisosteres.
Journal article
Kerckhoffs A. et al, (2026), Nat Chem
A posttranslational proteomic survey of a single anatomically preserved human 20-week postconception brain.
Journal article
Bandiera S. et al, (2026), J Anat
Combined middle meningeal artery embolisation and subdural evacuation port system drainage for chronic subdural haematoma: a systematic review, single-arm meta-analysis, meta-regression, and cost-benefit analysis.
Journal article
Nischal SA. et al, (2026), Clin Neurol Neurosurg, 264
Movements During Intended General Anesthesia and Psychologically Traumatic Accidental Awareness: Explanatory Role of the "Efference Copy Network".
Journal article
Pandit JJ., (2026), Anesth Analg, 142, 909 - 916
Opioid-free vs. opioid-inclusive anaesthesia with or without regional anaesthesia for postoperative pain: a systematic review with network meta-analysis of randomised controlled trials.
Journal article
de Carvalho CC. et al, (2026), Anaesthesia, 81, 702 - 712
Bionano Interface Optimization for Rational Lateral Flow Assay Development.
Journal article
Sadler CJ. et al, (2026), ACS Nano