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Oxford University researchers have discovered what causes a switch to flip in our brains and wake us up. The discovery, published in the journal Nature, brings us closer to understanding the mystery of sleep.
Human induced pluripotent stem cell-derived microglia with 1q21.1 deletion and duplication exhibit aberrant inflammatory response
Journal article
Singh T. et al, (2026), Genes and Diseases, 13
Injected extracellular vesicles and other nanoparticles hitchhike on erythrocytes and platelets from circulation towards organ clearance
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Pavlova S. et al, (2026), Extracellular Vesicle, 7
Opioid-free vs. opioid-inclusive anaesthesia with or without regional anaesthesia for postoperative pain: a systematic review with network meta-analysis of randomised controlled trials.
Journal article
de Carvalho CC. et al, (2026), Anaesthesia, 81, 702 - 712
Bionano Interface Optimization for Rational Lateral Flow Assay Development.
Journal article
Sadler CJ. et al, (2026), ACS Nano
Combined middle meningeal artery embolisation and subdural evacuation port system drainage for chronic subdural haematoma: a systematic review, single-arm meta-analysis, meta-regression, and cost-benefit analysis.
Journal article
Nischal SA. et al, (2026), Clin Neurol Neurosurg, 264
Movements During Intended General Anesthesia and Psychologically Traumatic Accidental Awareness: Explanatory Role of the "Efference Copy Network".
Journal article
Pandit JJ., (2026), Anesth Analg, 142, 909 - 916
Impaired glucose tolerance and mild diabetes induce β-cell dysfunction in mice.
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Haythorne E. et al, (2026), Nat Commun
The superior colliculus gates dopamine responses to conditioned stimuli in visual classical conditioning.
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Zhang Y-F. et al, (2026), Nat Commun
Faster and More Robust CK Reaction Rate Estimation at 3T Using Acquisition-Weighted 31P Cardiac 1D-MRSI With Compartment-Based Reconstruction.
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Axford A. et al, (2026), Magn Reson Med
Nipping Fraud in the Bud? Challenges for Detecting and Managing Issues of Research Integrity Before Publication.
Journal article
Haney MF. et al, (2026), Anesth Analg
TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network.
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Walth-Hummel AA. et al, (2026), Nat Commun, 17
The Basal Ganglia Upside Down: Non-Canonical Direct and Indirect Pathways Emerging from Striosomes Modulate Dopamine Release and Motor Behavior.
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Rocha GS. et al, (2026), J Neurophysiol
Towards automated joint detection in sleep studies: bridging clinical insight and artificial intelligence.
Journal article
Dorier A. et al, (2026), Sleep
Assessing the Metabolic Activity of Whole Regenerating Zebrafish Ventricles Ex Vivo Using an Extracellular Flux Assay.
Journal article
Lekkos K. et al, (2026), J Vis Exp
Epigenetic biomarkers in neurodegenerative diseases: from molecular signatures to therapeutic targets.
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Washer SJ. et al, (2026), Trends Neurosci
Biomarkers of Leucine-Rich Repeat Kinase 2 (LRRK2) and Lysosomal Dysfunction in Progressive Supranuclear Palsy.
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Nielsen L-K. et al, (2026), Mov Disord
Somatic mosaicism in ALS and FTD identifies focal mutations associated with widespread degeneration.
Journal article
Zhou Z. et al, (2026), Nat Genet
Pitch at the Cocktail Party: A Comparative Approach to Studying Selective Attention.
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Ward J. et al, (2026), Biology (Basel), 15
Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta-Cell Function.
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Lloyd M. et al, (2026), FASEB J, 40
Cluster-First Labelling: An Automated Pipeline for Segmentation and Morphological Clustering in Histology Whole Slide Images
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Ahmad MH. et al, (2026), arXiv