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Professor Roger Cox, Dr Dyan Sellayah and Professor Frances Ashcroft have discovered a previously unknown mechanism behind how the fat mass and obesity associated (FTO) gene promotes obesity. Their findings may have important implications for future therapeutic strategies to combat obesity.

Cerebral blood flow as a mechanistic framework across neurological disease

Journal article

Patel S. et al, (2026), Discover Neuroscience, 21

Dissecting genotype-specific effects of disease-associated genetic variants.

Journal article

Farrow SL. et al, (2026), iScience, 29

Reactive astrocytes mediate toxicity in iPSC derived dopaminergic neurons.

Journal article

Ibarra-Aizpurua N. et al, (2026), NPJ Parkinsons Dis

The seminal proteome of a monandrous fly, Drosophila subobscura.

Journal article

Dean R. et al, (2026), Proc Biol Sci, 293

Hypoxia differentially affects coronary vessel formation during heart development.

Journal article

Payne S. et al, (2026), Cardiovasc Res

GWAS on short tandem repeats identifies genetic mechanisms in Alzheimer's disease.

Journal article

Gmelin D. et al, (2026), Nat Commun, 17

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