This is an image of a mouse brain full-coronal section, which was obtained using spinning disk confocal microscopy. Red cells label remnants of the neurodevelopmental subplate–a critical structure which affects other cells through adulthood (e.g., cyan parvalbumin interneurons and magenta vicia villosa agglutinin perineural nets). Studying genetic manipulations in these subplate remnant cells implicates the structure as a substrate for neurodevelopmental origins of brain disease.
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Produced in collaboration with Florina Szabo, Oxford’s Cellular Imaging Core (WCHG), and the Eikholt Group (Charité University)