Research groups
Zhilian Hu
Ph.D.
Postdoctoral Research Scientist
- I completed my Ph.D. in 2012 in Developmental Biology from the University of Freiburg (Germany), where I focused on molecular mechanisms underlying defective dopaminergic systems of zebrafish in the laboratory of Prof. Wolfgang Driever. I moved to USA in 2013 to start my journey as a post-doctoral research fellow and my projects focused mainly on coagulation factor associated hemostatic disorders and effects of ECM molecules on abnormous development of endoderm/mesoderm derivatives including heart of zebrafish. In 2017, I was brought to Oxford by nice projects in the field of developmental and regenerative medicine, where I am immersing myself in the molecular events of fish heart regeneration in the laboratory of Prof. Mathilda Mommersteeg.
Recent publications
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Loss of fibrinogen in zebrafish results in an asymptomatic embryonic hemostatic defect and synthetic lethality with thrombocytopenia.
Journal article
Hu Z. et al, (2019), J Thromb Haemost, 17, 607 - 617
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Heart Regeneration in the Mexican Cavefish.
Journal article
Stockdale WT. et al, (2018), Cell Rep, 25, 1997 - 2007.e7
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Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function
Journal article
Liu Y. et al, Blood, 124, 142 - 150
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Loss of DDB1 Leads to Transcriptional p53Pathway Activation in Proliferating Cells,Cell Cycle Deregulation, and Apoptosis inZebrafish Embryos
Journal article
HU Z. et al, PLoS One
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Genome editing of factor X in zebrafish reveals unexpected tolerance of severe defects in the common pathway
Journal article
Hu Z. et al, Blood, 130, 666 - 676