Zhilian Hu

Ph.D.

Postdoctoral Research Scientist

I completed my Ph.D. in Developmental Biology from the University of Freiburg (Germany), where I focused on molecular mechanisms underlying defective dopaminergic systems of zebrafish in the laboratory of Prof. Driever. Then I moved to USA to start my journey as a post-doctoral research fellow and my projects focused mainly on coagulation factor associated hemostatic disorders and effects of ECM molecules on abnormous development of endoderm/mesoderm derivatives including heart of zebrafish. In 2017, I was brought to Oxford by nice projects in the field of developmental and regenerative medicine, where I am immersing myself in the molecular events of fish heart regeneration.

Recent publications

Disruption of the kringle 1 domain of prothrombin leads to late onset mortality in zebrafish.
Journal article

Grzegorski SJ. et al, (2020), Sci Rep, 10
Loss of fibrinogen in zebrafish results in an asymptomatic embryonic hemostatic defect and synthetic lethality with thrombocytopenia.
Journal article

Hu Z. et al, (2019), J Thromb Haemost, 17, 607 - 617
Heart Regeneration in the Mexican Cavefish.
Journal article

Stockdale WT. et al, (2018), Cell Rep, 25, 1997 - 2007.e7
Genome editing of factor X in zebrafish reveals unexpected tolerance of severe defects in the common pathway
Journal article

Hu Z. et al, Blood, 130, 666 - 676
Loss of DDB1 Leads to Transcriptional p53Pathway Activation in Proliferating Cells,Cell Cycle Deregulation, and Apoptosis inZebrafish Embryos
Journal article

HU Z. et al, PLoS One

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