Zeinab is interested in understanding the role of metabolic disturbances in amyotrophic lateral sclerosis (ALS). Metabolic alterations have been reported in a number of neurodegenerative disorders as a consequence of the disease. However, recent research shows that these alterations occur before disease onset and may be integral to early pathomechanisms. Zeinab’s focus is in understanding lipid metabolism dysregulation. She is using a multi-disciplinary approach to isolate lipid biology pathways that are altered in a pre-symptomatic in vivo model of ALS e.g. RNA-sequencing, lipidomics and CARS microscopy.
Zeinab obtained her MSci in Integrative Physiology and Pharmacology at King’s College London. She undertook a placement year in a biopharmaceutical company, Union Chimique Belge, identifying novel mediators involved in atopic dermatitis. She is currently working on her DPhil project in the group of Professor Elizabeth Fisher, under the supervision of Dr Tom Cunningham and Dr Silvia Corrochano.