Convergent large-scale network and local vulnerabilities underlie brain atrophy across Parkinson's disease stages: a worldwide ENIGMA study.

Vo A., Tremblay C., Rahayel S., Al-Bachari S., Berendse HW., Bright JK., Cendes F., d'Angremont E., Dalrymple-Alford JC., Debove I., Dirkx MF., Druzgal J., Garraux G., Helmich RC., Hu M., Jahanshad N., Johansson ME., Klein JC., Laansma MA., McMillan CT., Melzer TR., Misic B., Mosley P., Owens-Walton C., Parkes LM., Pellicano C., Piras F., Poston KL., Rango M., Rummel C., Schwingenschuh P., Suette M., Thompson PM., Tosun D., Tsai C-C., van Balkom TD., van den Heuvel OA., van der Werf YD., van Heese EM., Vriend C., Wang J-J., Wiest R., Yasuda C., Dagher A., ENIGMA-Parkinson’s Study .

DOI

10.1101/2025.05.25.25326586

Type

Preprint

Publication Date

2025-05-29T00:00:00+00:00

Keywords

Parkinson’s disease, connectivity, imaging transcriptomics, neurodegeneration, structural MRI

Permalink More information Close