D.Phil. / PhD
Postdoctoral Research Scientist
Identifying drugs to stimulate endogenous cardiac progenitor cells for heart regeneration after infarction
Sophia Malandraki-Miller studied Applied Biology & Biotechnology at University of Ioannina, in Greece.
She then completed her PhD/ DPhil studies in Department of Physiology, Anatomy & Genetics - University of Oxford in Prof. Carolyn Carr's group. Her research was conducted on cardiac progenitor cells (isolation methods, metabolism, differentiation, and miRNA pre-conditioning) and stem cell therapy.
In 2017 she started as a Postdoctoral Research Scientist in Prof. Paul Riley’s group at DPAG, jointly working for Oxstem, a University of Oxford spin-out focusing on stem cell drug discovery.
She is currently investigating the activation of adult endogenous epicardial progenitor cells, using small molecules, with the ultimate goal to treat myocardial infarction.
S Malandraki-Miller, CA Lopez, R Alonaizan, U Purnama, F Perbellini, K Pakzad, CA Carr, Metabolic flux analyses to assess the differentiation of adult cardiac progenitors after fatty acid supplementation. Stem Cell Research 2019; Volume 38, 101458. https://doi.org/10.1016/j.scr.2019.101458
Malandraki-Miller S, Lopez CA, Al-Siddiqi H, Carr CA. Changing Metabolism in Differentiating Cardiac Progenitor Cells-Can Stem Cells Become Metabolically Flexible Cardiomyocytes?. Front Cardiovasc Med. 2018;5:119. doi:10.3389/fcvm.2018.00119