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Research groups

Sophia Malandraki-Miller

D.Phil. / PhD


Postdoctoral Research Scientist

Identifying drugs to stimulate endogenous cardiac progenitor cells for heart regeneration after infarction

Sophia Malandraki-Miller studied Applied Biology & Biotechnology at University of Ioannina, in Greece.

She then completed her PhD/ DPhil studies in Department of Physiology, Anatomy & Genetics - University of Oxford in Prof. Carolyn Carr's group. Her research was conducted on cardiac progenitor cells (isolation methods, metabolism, differentiation, and miRNA pre-conditioning) and stem cell therapy.

In 2017 she started as a Postdoctoral Research Scientist in Prof. Paul Riley’s group at DPAG, jointly working for Oxstem, a University of Oxford spin-out focusing on stem cell drug discovery.

She is currently investigating the activation of adult endogenous epicardial progenitor cells, using small molecules, with the ultimate goal to treat myocardial infarction.

PUBLICATIONS

S Malandraki-Miller, CA Lopez, R Alonaizan, U Purnama, F Perbellini, K Pakzad, CA Carr, Metabolic flux analyses to assess the differentiation of adult cardiac progenitors after fatty acid supplementation. Stem Cell Research 2019; Volume 38, 101458. https://doi.org/10.1016/j.scr.2019.101458


Malandraki-Miller S, Lopez CA, Al-Siddiqi H, Carr CA. Changing Metabolism in Differentiating Cardiac Progenitor Cells-Can Stem Cells Become Metabolically Flexible Cardiomyocytes?. Front Cardiovasc Med. 2018;5:119. doi:10.3389/fcvm.2018.00119