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- Molnar Group Research Group
I am a post-doctoral fellow in the group of Professor Zoltán Molnár’s laboratory. My general research interests are in dynamic cell-cell interactions that are mediated by cell surface proteins and the cytoskeleton in brain development. Through my previous and current postdoctoral studies, I have been particularly interested in the molecular mechanism underlying neuronal wiring specificity and plasticity. My current research focuses on the cerebral cortex and its connectivity with subcortical regions.
I completed my PhD on the regulation of sperm tail movement, focusing on the mechanical force-dependent switching of dynein activity in flagella, at the University of Tokyo under the supervision of Professor Chikako Shingyoji. I did my post-doctoral research on the role of non-clustered protocadherins in brain development at the RIKEN Center for Developmental Biology (CDB) under the supervision of Professor Masatoshi Takeichi. In 2016 I joined the Molnár Group, undertaking research on the ultrastructural characterisation of corticothalamic axon terminals in thalamic nuclei by using electron microscopy. I am also working on activity-dependent plasticity of the neonatal thalamus.
Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice.
Hayashi S. et al, (2017), Sci Rep, 7
Emerging roles of protocadherins: from self-avoidance to enhancement of motility.
Hayashi S. and Takeichi M., (2015), J Cell Sci, 128, 1455 - 1464
Protocadherin-17 mediates collective axon extension by recruiting actin regulator complexes to interaxonal contacts.
Hayashi S. et al, (2014), Dev Cell, 30, 673 - 687
Bending-induced switching of dynein activity in elastase-treated axonemes of sea urchin sperm--roles of Ca2+ and ADP.
Hayashi S. and Shingyoji C., (2009), Cell Motil Cytoskeleton, 66, 292 - 301
Mechanism of flagellar oscillation-bending-induced switching of dynein activity in elastase-treated axonemes of sea urchin sperm.
Hayashi S. and Shingyoji C., (2008), J Cell Sci, 121, 2833 - 2843
Expression patterns of Xenopus FGF receptor-like 1/nou-darake in early Xenopus development resemble those of planarian nou-darake and Xenopus FGF8.
Hayashi S. et al, (2004), Dev Dyn, 230, 700 - 707