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Rosie Little

DPhil Student

I am a Medical Research Council funded DPhil student working in the Cilia, Development and Disease group at the Mammalian Genetics Unit, MRC Harwell Institute. One of the interest within the group is understanding the genetic and molecular mechanism of left-right patterning using the mouse embryo as a model. My project focuses on the role of FGF signalling in this process, and also on understanding the mechanism by which left-right symmetry is initially broken in the developing embryo. I use embryonic culture techniques along with gene expression and protein analysis, along with mutant phenotyping using SEM. 

I graduated from Cardiff University in 2016 with a BSc (Hons) in Genetics (4 years including Professional Training Year). This included spending a year in the Behavioural Genetics Group at the MRC Centre for Neuropsychiatric Genetics and Genomics, where I worked on CNVs and imprinted genes.